Advancing Prion Science - download pdf or read online

By Committee on Transmissible Spongiform Encephalopathies: Assessment of Relevant Science

ISBN-10: 0309087449

ISBN-13: 9780309087445

ISBN-10: 0309504406

ISBN-13: 9780309504409

Meantime file of the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies: evaluate of correct technological know-how, convened to supply suggestion to the U.S. division of protection concerning prion affliction. makes a speciality of the learn had to enhance diagnostics for prion illnesses and discusses prion study infrastructure concerns. Softcover.

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1968. Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee. Science 161(839):388-389. Glasse R. 1967. Cannibalism in the kuru region of New Guinea. Transactions of the New York Academy of Sciences 29:748-754. Godon KA, Honstead J. 1998. Transmissible spongiform encephalopathies in food animals. Human food safety and animal feed safety concerns for veterinarians. Veterinary Clinics of North America. Food Animal Practice 14(1):49-70. Griffith, J. S. 1967. Self-replication and scrapie.

S. Army Medical Research and Materiel Command. Senate Committee on Appropriations. 2001. Senate Report 107-109. Department of Defense Appropriation Bill, 2002 and Supplemental Appropriations, 2002. Title VI. R. 3338. S. Congress. IOM (Institute of Medicine). 1993. S. Army Medical Research and Development Command. IOM Committee to Advise the Department of Defense on its Fiscal Year 1993 Breast Cancer Program. : National Academy Press. 2 Prion Diseases and Their Challenges ORIGINS AND DEVELOPMENT OF PRION SCIENCE The identification of a previously unknown malady in the Fore Tribe of Papua New Guinea drew international attention to the group of brain-wasting diseases called transmissible spongiform encephalopathies (TSEs).

TABLE 2-1 Classification of TSEs Modes of Natural Transmission Date First Recognized Sporadic Creutzfeldt-Jakob disease (sCJD) Unknown 1920 Sporadic fatal insomnia (sFI) Unknown 1999 Familial Creutzfeldt-Jakob disease Genetic 1924a Fatal familial insomnia (FFI) Genetic 1986b Gerstmann-Straussler-Scheinker disease Genetic 1936c Kuru Exposure to contaminated human tissues during endocannibalistic rituals 1957 Iatrogenic Creutzfeldt-Jakob disease CJD-infected surgical equipment or tissue transplants 1974d Variant Creutzfeldt-Jakob disease (vCJD) Eating BSE-infected tissue; other modese 1996 Type of TSE Affected Mammals In humans 27 28 TABLE 2-1 Classification of TSEs (continued) Affected Mammals Modes of Natural Transmission Date First Recognized Scrapie Sheep, goats Contact with infected placenta; possibly oral exposure to environmental contamination 18th century Transmissible mink encephalopathy Mink Eating infected tissue 1947 Chronic wasting disease Deer, elk Unknown; likely oral 1967 Bovine spongiform encephalopathy (BSE) Cattle Eating TSE-infected tissue 1986 Nyala, gemsbok, Arabian oryx, eland, kudu, scimtarhorned oryx, puma, cheetah, ocelot, tigerf Eating BSE-infected tissue Mid-1980s Domestic catg Eating BSE-infected tissue 1990 Type of TSE In animals a Gambetti et al.

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Advancing Prion Science by Committee on Transmissible Spongiform Encephalopathies: Assessment of Relevant Science


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